Changbin Shi Selected Research

Central Nervous System Cavernous Hemangioma

12/2022	Cerebral cavernous malformation development in chronic mouse models driven by dual recombinases induced gene deletion in brain endothelial cells.
1/2020	Antibodies in cerebral cavernous malformations react with cytoskeleton autoantigens in the lesional milieu.
1/2018	Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations.
1/2018	Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth.
7/2017	Vascular permeability and iron deposition biomarkers in longitudinal follow-up of cerebral cavernous malformations.
1/2017	RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
1/2016	Micro-computed tomography in murine models of cerebral cavernous malformations as a paradigm for brain disease.
1/2016	B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models.
1/2016	Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease.
3/2015	Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations.

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Changbin Shi Research Topics

Disease

15	Central Nervous System Cavernous Hemangioma 12/2022 - 05/2009
6	Neoplasms (Cancer) 03/2016 - 07/2002
5	Glioma (Gliomas) 03/2016 - 07/2002
5	Pancreatitis 06/2007 - 01/2005
4	Hemorrhage 01/2019 - 02/2012
4	Inflammation (Inflammations) 01/2018 - 11/2007
3	Glioblastoma (Glioblastoma Multiforme) 06/2013 - 07/2002
2	Lung Injury 05/2006 - 03/2005
1	Neurologic Manifestations (Neurological Manifestations) 12/2022
1	Breast Neoplasms (Breast Cancer) 11/2020
1	Cavernous Hemangioma (Cavernous Angioma) 01/2019
1	Acute Disease 01/2018
1	Disease Progression 01/2018
1	Seizures (Absence Seizure) 01/2018
1	Traumatic Brain Injuries (Traumatic Brain Injury) 07/2017
1	Body Weight Changes 03/2016
1	Vascular Malformations 01/2016
1	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 08/2010
1	Intracranial Vasospasm 08/2010
1	Arteriovenous Malformations (Arteriovenous Malformation) 11/2007
1	Ascites 06/2007
1	Acute Lung Injury 05/2006
1	Sepsis (Septicemia) 03/2005
1	Leukemia 07/2002
1	Acute Promyelocytic Leukemia 07/2002

Drug/Important Bio-Agent (IBA)

7	Biomarkers (Surrogate Marker)IBA 01/2019 - 02/2012
5	IronIBA 07/2017 - 02/2014
4	Therapeutic UsesIBA 11/2020 - 09/2011
3	MicroRNAs (MicroRNA)IBA 01/2019 - 10/2011
3	rho-Associated KinasesIBA 01/2016 - 02/2012
3	Arsenic Trioxide (Trisenox)FDA Link 06/2013 - 07/2002
2	Pharmaceutical PreparationsIBA 12/2022 - 07/2002
2	Immunoglobulin G (IgG)IBA 01/2020 - 11/2007
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2020 - 07/2014
2	fasudil (AT 877)IBA 01/2017 - 02/2012
2	Proteins (Proteins, Gene)FDA Link 10/2011 - 01/2005
2	AntigensIBA 05/2009 - 11/2007
2	Interleukin-10 (Interleukin 10)IBA 06/2007 - 05/2006
2	Peptide Hydrolases (Proteases)FDA Link 06/2007 - 05/2006
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2006 - 03/2005
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2005 - 01/2005
1	Recombinases (Recombinase)IBA 12/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2020
1	Everolimus FDA Link 11/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 11/2020
1	AntibodiesIBA 01/2020
1	Complement System Proteins (Complement)IBA 01/2020
1	AutoantigensIBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2017
1	Simvastatin (Zocor)FDA LinkGeneric 01/2017
1	FlavonoidsIBA 03/2016
1	QuercetinIBA 03/2016
1	HDL CholesterolIBA 01/2016
1	Heme (Haem)IBA 01/2016
1	Vitamin D FDA LinkGeneric 01/2016
1	PorphyrinsIBA 01/2013
1	AcidsIBA 01/2013
1	Small Untranslated RNAIBA 10/2011
1	Heme Oxygenase-1IBA 09/2011
1	pimagedine (aminoguanidine)IBA 08/2010
1	Immunoglobulins (Immunoglobulin)IBA 05/2009
1	Interleukin-6 (Interleukin 6)IBA 06/2007
1	Peroxidase (Myeloperoxidase)IBA 06/2007
1	Phospholipases (Phospholipase)IBA 06/2007
1	Protease Inhibitors (Protease Inhibitor)IBA 06/2007
1	Interleukin-2 (IL2)IBA 05/2006
1	Protein Kinase CIBA 05/2006
1	Tissue Inhibitor of Metalloproteinase-1IBA 05/2006
1	Polymyxin B (Aerosporin)FDA LinkGeneric 05/2006
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 03/2005
1	NF-kappa B (NF-kB)IBA 01/2005
1	CytokinesIBA 01/2005
1	Antineoplastic Agents (Antineoplastics)IBA 07/2002
1	CyclinsIBA 07/2002

Therapy/Procedure

2	Therapeutics 03/2016 - 01/2016
1	Ligation 03/2005
1	Punctures 03/2005